CASP14 monoclonal antibody (M01), clone 4C9
产品名称: CASP14 monoclonal antibody (M01), clone 4C9
英文名称: CASP14 monoclonal antibody (M01), clone 4C9
产品编号: H00023581-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant CASP14.
- Immunogen:
- CASP14 (NP_036246, 133 a.a. ~ 242 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- RGEQRDPGETVGGDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKRKGHILELLTEVTRRMAEAELVQEGKARKTNPEIQSTLRKRLYLQ
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Cell lysate)
- CASP14 monoclonal antibody (M01), clone 4C9 Western Blot analysis of CASP14 expression in MCF-7 ( Cat # L046V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
- enlarge this image
- Immunofluorescence of monoclonal antibody to CASP14 on HeLa cell. [antibody concentration 15 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CASP14 is approximately 1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 23581
- GeneBank Accession#:
- NM_012114
- Protein Accession#:
- NP_036246
- Gene Name:
- CASP14
- Gene Alias:
- MGC119078,MGC119079
- Gene Description:
- caspase 14, apoptosis-related cysteine peptidase
- Omim ID:
- 605848
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq
- Other Designations:
- apoptosis-related cysteine protease,caspase 14,caspase 14, apoptosis-related cysteine protease
- Related Disease
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Colorectal Neoplasms
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Liver Neoplasms
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Occupational Diseases
- Prostatic Neoplasms
- Stomach Neoplasms
- Waldenstrom Macroglobulinemia
- Werner syndrome