STK39 polyclonal antibody
产品名称： STK39 polyclonal antibody
英文名称： STK39 polyclonal antibody
产品编号： PAB16584
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of STK39.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 19 amino acids of human STK39.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.
Gagnon KB, England R, Delpire E.Mol Cell Biol. 2006 Jan;26(2):689-98.
- 2.
- SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway.
Li Y, Hu J, Vita R, Sun B, Tabata H, Altman A.EMBO J. 2004 Mar 10;23(5):1112-22. Epub 2004 Feb 26.
- 3.
- The Ste20 group kinases as regulators of MAP kinase cascades.
Dan I, Watanabe NM, Kusumi A.Trends Cell Biol. 2001 May;11(5):220-30.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of STK39 in SK-N-SH cell lysate with STK39 polyclonal antibody (Cat # PAB16584) at (A) 1 and (B) 2 ug/mL .
- Entrez GeneID:
- 27347
- Protein Accession#:
- NP_037365
- Gene Name:
- STK39
- Gene Alias:
- DCHT,DKFZp686K05124,PASK,SPAK
- Gene Description:
- serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
- Omim ID:
- 607648
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq
- Other Designations:
- Ste20-like protein kinase,proline-alanine-rich STE20-related kinase,small intestine SPAK-like kinase