Murine & Rat Growth Factors & Cytokines
Recombinant Murine FGF-acidic


 
 
Synonyms :
Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
Description :
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
Catalog #:
450-33A
Source :
E.coli
Purity :
Greater than 95% by SDS-PAGE gel and HPLC analyses
Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Biological Activity :
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of heparin is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg. 

Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.2 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Selected References :
Selected List of References Citing This PeproTech Product
AA Sequence :
MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D 
PubMed Link :
murine+AND+FGF+AND+Acidic
Country of Origin :
USA
 
 
Size A
10μg
$80 
 
 
Size B
50μg
$195 
 
 
Size C
1mg
$1500 
 
 
 
 
Special Sizes: 
Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.
 
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.