GRN purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： GRN purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： GRN purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00002896-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human GRN protein.
- Immunogen:
- GRN (NP_002078.1, 1 a.a. ~ 593 a.a) full-length human protein.
- Sequence:
- MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- GRN MaxPab rabbit polyclonal antibody. Western Blot analysis of GRN expression in mouse testis.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of GRN expression in transfected 293T cell line (H00002896-T01) by GRN MaxPab polyclonal antibody.
Lane 1: GRN transfected lysate(63.50 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 2896
- GeneBank Accession#:
- NM_002087
- Protein Accession#:
- NP_002078.1
- Gene Name:
- GRN
- Gene Alias:
- GEP,GP88,PCDGF,PEPI,PGRN
- Gene Description:
- granulin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq
- Other Designations:
- PC cell-derived growth factor,acrogranin,granulin-epithelin,proepithelin,progranulin
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Aphasia
- Aphasia, Primary Progressive
- Atrophy
- Cardiovascular Diseases
- Cognition
- Dementia
- Diabetes Mellitus, Type 2
- Edema
- Frontotemporal Dementia
- Frontotemporal Lobar Degeneration
- Genetic Predisposition to Disease
- Memory
- Memory Disorders
- Motor Neuron Disease
- Movement Disorders