Anti-TLR7 Monoclonal Antibody

英文名称	Anti-TLR7 Monoclonal Antibody
别名	TLR7-like;toll-like receptor 7
应用	WB
稀释比例	WB 1:1000.
蛋白分子量	121kDa
Gene ID	51284
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human TLR7 protein fragments expressed in E.coli.
性状	液体
Subcellular Locations	Cytoplasmic vesicle Endoplasmic reticulum membrane Endosome Lysosome Single-pass type I membrane protein phagosome
Swiss Prot	Q9NYK1
克隆号	3F11-2C9-D8
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.