FITC标记的SNAPC3蛋白抗体
产品名称： FITC标记的SNAPC3蛋白抗体
英文名称： Anti-SNAPC3/FITC
产品编号： HZ-8452R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-SNAPC3/FITC Conjugated antibody
FITC标记的SNAPC3蛋白抗体
| 产品编号 | bs-8452R-FITC |
| 英文名称 | Anti-SNAPC3/FITC |
| 中文名称 | FITC标记的SNAPC3蛋白抗体 |
| 别 名 | SNAP50; SNAPc50; Proximal sequence element-binding transcription factor subunit beta; PSE binding factor subunit beta; PTF subunit beta; PTFbeta; small nuclear RNA activating complex, polypeptide 3, 50kDa; Small nuclear RNA-activating complex polypeptide 3; SNAPc 50 kDa subunit; SNAPc subunit 3; snRNA activating protein complex 50 kDa subunit; snRNA activating protein complex subunit 3; SNPC3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNAPC3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box. Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. Subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1. Subcellular Location: Nuclear Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Database links: Entrez Gene: 6619 Human Entrez Gene: 77634 Mouse Entrez Gene: 362537 Rat Omim: 602348 Human SwissProt: Q92966 Human SwissProt: Q9D2C9 Mouse SwissProt: Q5BK68 Rat Unigene: 546299 Human Unigene: 271985 Mouse Unigene: 482328 Mouse Unigene: 204909 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SNAPC3是RNA聚合酶II和III小核RNA基因转录所需的SNAPC复合物的一部分。SNAPC3与近端序列元件（PSE）结合，这是这2种基因共同的非TATA盒基础启动子元件。SNAPC3将TBP和BRF2招募到U6SNRNA TATA盒。