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上海信裕生物科技有限公司
HDAC2-specific抗体

HDAC2-specific抗体

商家询价

产品名称: HDAC2-specific抗体

英文名称: HDAC2-specificAntibody

产品编号: XY16152-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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  • 邮编 : 200612
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 HDAC2-SPECIFIC抗体

Applications
In-house applications ELISA, WB, IHC, IF, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev12NextView more validation data
  • 16152-1-AP;HepG2 cellsHepG2 cells were subjected to SDS PAGE followed by western blot with 16152-1-AP(HDAC2-specific antibody) at dilution of 1:500
  • 16152-1-AP;human testisImmunohistochemical of paraffin-embedded human testis using 16152-1-AP(HDAC2-specific antibody) at dilution of 1:50 (under 10x lens)
  • 16152-1-AP;human testisImmunohistochemical of paraffin-embedded human testis using 16152-1-AP(HDAC2-specific antibody) at dilution of 1:50 (under 40x lens)
  • 16152-1-AP;HeLa cellsImmunofluorescent analysis of HeLa cells using 16152-1-AP( HDAC2-specific Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
  • 16152-1-AP;A431 cellsIP Result of anti-HDAC2-specific (IP:16152-1-AP, 4ug; Detection:16152-1-AP 1:500) with A431 cells lysate 2400ug.
Positive WB detected in HepG2 cells, A431 cells, HeLa cells, human liver tissue
Positive IP detected in A431 cells
Positive IHC detected in Human testis tissue, human brain tissue, human heart tissue, human kidney tissue, human liver tissue, human ovary tissue, human skin tissue, human spleen tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100
 HDAC2-SPECIFIC抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Peptide Full name Histone deacetylase 2
Calculated molecular
weight
55 kDa Observed molecular 
weight
55 kDa
GenBank accession 
number
NM_001527 Gene ID (NCBI) 3066
Gene symbol HDAC2 Synonyms HD2, HDAC2, histone deacetylase 2, RPD3, YAF1
Background HDAC2-SPECIFIC抗体

Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin.Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). At least 4 classes of HDAC were identified. As a class I HDAC, HDAC2 was primarily found in the nucleus. HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human HDAC2 and is specific to HDAC2. It will not cross react with other HDACs. HDAC2-SPECIFIC抗体

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