HAX1 monoclonal antibody, clone 9G3D11
产品名称： HAX1 monoclonal antibody, clone 9G3D11
英文名称： HAX1 monoclonal antibody, clone 9G3D11
产品编号： MAB7876
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of HAX1.
- Immunogen:
- A synthetic peptide corresponding to N-terminus 15 amino acids of human HAX1.
- Host:
- Mouse
- Reactivity:
- Human, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons.
Chao JR, Parganas E, Boyd K, Hong CY, Opferman JT, Ihle JN.Nature. 2008 Mar 6;452(7183):98-102. Epub 2008 Feb 20.
- 2.
- Human immunodeficiency virus type 1 Vpr interacts with antiapoptotic mitochondrial protein HAX-1.
Yedavalli VS, Shih HM, Chiang YP, Lu CY, Chang LY, Chen MY, Chuang CY, Dayton AI, Jeang KT, Huang LM.J Virol. 2005 Nov;79(21):13735-46.
- 3.
- K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function.
Sharp TV, Wang HW, Koumi A, Hollyman D, Endo Y, Ye H, Du MQ, Boshoff C.J Virol. 2002 Jan;76(2):802-16.
- Entrez GeneID:
- 10456
- Protein Accession#:
- NP_006109
- Gene Name:
- HAX1
- Gene Alias:
- FLJ17042,FLJ18492,FLJ93803,HCLSBP1,HS1BP1,SCN3
- Gene Description:
- HCLS1 associated protein X-1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- HCLS1 (and PKD2) associated protein,HS1 binding protein,OTTHUMP00000034190
- Related Disease